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News releases

  • Program simulates the behavior of thousand-strong crowds

    Simulator computes evacuation scenarios for major events

    The simulation represents every individual in a ten-thousand crowd. (Photo: REPKA / TUM)

    Predicting how large numbers of visitors to major events will behave is difficult, even using evidence based on past experience. To prevent disasters, however, the police, rescue services and event organizers have to be able to identify dangerous bottlenecks, hidden obstacles and unexpected escape routes in advance. A research group with engineers and computer scientists at Technische Universität München (TUM) has developed a simulator that can be used to compute different scenarios at specific venues. The program can simulate the behavior of tens of thousands of people, making emergency management significantly easier.

  • Saving data in vortex structures:

    New physical phenomenon could drastically reduce energy consumption by computers

    A grid of magnetic vortex structures

    Faster, smaller and more energy-efficient – that is what computers of the future should be like. A new phenomenon stands to make a major contribution in this direction: It needs 100,000 times less current than existing technologies, and the number of atoms needed for a data bit could diminish significantly. A team of physicists from the Technische Universität München (TUM) and the University of Cologne are driving this technology forward. They have now developed a simple electronic method for moving and reading data bits. The journal Nature Physics reports on their results.

  • Molecular basis for the development of new drugs against autoimmune diseases:

    Determination of the immunoproteasome crystal structure

    Immunoproteasome

    Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells that due to a viral infection present non-self peptides at their surface. In autoimmune diseases this mechanism is deregulated and the immune system also eliminates uninfected cells by mistake. However, inhibition of the immunoproteasome may alleviate disease symptoms and progression. Biochemists at the Technische Universitaet Muenchen (TUM) now succeeded in determining the first crystal structure of an immunoproteasome. The results are reported in the renowned journal "Cell" and will enable the development of new drugs that selectively target the immunoproteasome.

  • Scientists discover new approach for cancer medication

    New class of drugs for the reversible inhibition of proteasomes

    A hydroxyurea derivative blocks the proteasome

    As the "recycling plant" of the cell, the proteasome regulates vitally important functions. When it is inhibited, the cell chokes on its own waste. Cancer cells, in particular, are very sensitive because they need the proteasome for their uncontrolled growth. Biochemists at the Technische Universitaet Muenchen (TUM) have now identified the lead structure of a new class of drugs that attacks the proteasome in an unusual way. New medication could be developed on the basis of this previously unknown binding mechanism. The scientists report their results in the scientific journal "Angewandte Chemie".

  • New research center for translational oncology (TranslaTUM) to be built at University Hospital Klinikum rechts der Isar

    New TranslaTUM research center to promote cancer research

    The modern resesearch center TranslaTUM is scheduled for completion by the end of 2016. The picture shows a simulation of the building. (Image: doranth post architekten)

    A research center for translational oncology (TranslaTUM) is being built at the Munich location. The Joint Science Conference (Gemeinsame Wissenschaftskonferenz, GWK), established by the German Federal Government and the Federal States has now given the green light to the funding application submitted by Technical University of Munich (TUM). The purpose of the center is to improve the chances of a cure for cancer patients by developing and applying (translating) new methods.

  • TU München presents its electromobility vehicle concept MUTE

    MUTE: the efficient city car

    MUTE – the efficient city car

    With its electric vehicle MUTE, the Technische Universität München (TUM) presents the first publicly visible result of its research program TUM.Energy. MUTE will showcase the TUM’s answer to future challenges in personal mobility at the International Motor Show (IAA) in Frankfurt. MUTE is a purely electric, energy-efficient vehicle that meets all requirements of a full-fledged car. With MUTE, the 20 involved departments present a strategy for manufacturing a mass-production vehicle at an overall cost on par with that of comparable combustion engine vehicles.

  • Interaction between tumor suppressor protein and chaperone revealed:

    A chaperone for the “guardian of the genome”

    HSP90 protects p53 at risk.

    The protein p53 plays an essential role in the prevention of cancer by initiating the controlled death of a cell with damaged genes which is in danger to transform into a cancerous cell. The heat shock protein Hsp90, in turn, activates and stabilizes p53. Now scientists of the Technische Universität München (TUM) have discovered both the site where the two proteins interact and the interaction mechanism. The results of their work are reported in the current edition of the publication Nature Structural and Molecular Biology.

  • Researchers in mathematics education at TU Munich confirm the success of child-led learning

    Schoolchildren can also learn complex subject matters on their own

    Two Students studying

    Self-directed learning has long been heralded as the key to successful education. Yet until now, there has been little research into this theory. Educational researchers at the Technical University of Munich (TUM) have now shown that schoolchildren can independently develop strategies for solving complex mathematical tasks, with weaker students proving just as capable as their stronger class mates.

  • For the first time, investigating the heart as a whole

    Artificial nanoparticles influence the heart rate

    Artificial nanoparticles are becoming increasingly pervasive in modern life. However, their influence on our health and the mechanisms by which they affect the human body remain largely shrouded in mystery. Using a so-called Langendorff heart, a team of scientist from the Technische Universität München (TUM) and the Helmholtz Zentrum München has now for the first time shown that selected artificial nanoparticles have a direct effect on heart rate and heart rhythm. The scientists are presenting their results in the journal ACSNano.

  • Fundamental biology

    TUM researchers discover a new switch in resistance to plant diseases

    Powdery mildew is a tricky pathogen: The fungus can manipulate barley in a way that it is not only granted entry into the plant, but also gets the plant’s cells to supply it with nutrients. A team of researchers at the Chair of Phytopathology at Technische Universitaet Muenchen (TUM) has just identified, on a molecular level, how the fungus manages this feat – and how barley can fight back. The results have now been published in the renowned journal "The Plant Cell".

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D-80333 Munich
Tel. +49 89 289 22778
Fax +49 89 289 23388
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Further Information

Contact

Corporate Communications Center
Technical University of Munich
Arcisstr. 21
D-80333 Munich
Tel. +49 89 289 22778
Fax +49 89 289 23388
presse@tum.de

www.tum.de/presse