TUM – Latest news https://www.tum.de Latest news of TUM en TUM Tue, 18 Feb 2020 14:45:30 +0100 Tue, 18 Feb 2020 14:45:30 +0100 "Challenge your political and business leaders" https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35913/ "I am urging you today to challenge your political and business leaders!" Ban Ki-moon told approximately 1,000 students in the main auditorium on Friday evening. "Only activism will make sure that your leaders will follow your voices." He added that the generation that is growing up in the digital age instinctively understand that people all over the world are linked with one another as global citizens, but that several of the most powerful states are attacking the principles of the United Nations.

Ban, Secretary General of the UN from 2007 to 2016, aimed particular criticism at the US government for its withdrawal from the nuclear agreement with Iran, from the INF disarmament treaty and the Paris agreement on climate change. Ban said that nuclear armament and climate change are currently the greatest dangers to the world, and the multilateral system is the best way to master them.

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Campus news klaus.becker@tum.de news-35913 Mon, 17 Feb 2020 08:17:37 +0100
Lane change in the cytoskeleton https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35911/ All cells of higher organisms are permeated by a cytoskeleton that essentially consists of actin filaments and small protein tubes called microtubules. For a long time science considered the actin or microtubule networks as independent systems.

Today it is known that the two network types communicate with each other and thereby make vital cellular processes such as cell division or cell migration possible in the first place. However, it was still unknown how this collaboration works at the molecular level.

Dr. Zeynep Ökten from the Chair of Molecular Biophysics at the Technical University of Munich (TUM) and Erwin Frey, Professor of Statistical and Biological Physics at the Ludwig-Maximilians-Universität München – with their teams – have now for the first time identified a molecular mechanism by the example of change of color among animals which explains the communication between both network systems, and revealed potential evolutionary paths.

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Research news battenberg@zv.tum.de news-35911 Wed, 12 Feb 2020 09:01:55 +0100
No exams on February 10, 2020 https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35909/ Campus news news-35909 Mon, 10 Feb 2020 09:18:34 +0100 Major project for Munich neurosciences https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35907/ "The goals of the project are to better diagnose severe neurological disorders, to understand their molecular causes and to monitor the course of therapy. High-performance mass spectrometry can make a decisive contribution to this", explains Prof. Bernhard Küster, professor of proteomics and bioanalysis at the Technical University of Munich (TUM) and co-spokesperson of the research consortium.

Mass spectrometry permits the simultaneous and quantitative determination of minute quantities of thousands of biomolecules from tissues or body fluids. Such molecular profiles for proteins will now be brought into clinical use for the first time.

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Research news katharina.baumeister@tum.de news-35907 Mon, 10 Feb 2020 10:15:00 +0100
"Cities are increasingly reaching their limits" https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35857/ Professor Drewes, where does our drinking water come from?

Most drinking water in Germany is taken from groundwater. This is ideal, since the natural subsurface already filters out pathogens and harmful substances from the water. And groundwater resources are well protected and relatively stable with regard to environmental factors such as temperature. But groundwater resources are limited at many locations in Germany. In these cases the groundwater is artificially augmented with surface water from rivers or lakes, or drinking water is acquired directly from large surface water reservoirs.

Is the amount of water in Germany constantly dropping?

Extreme weather events like floods and extended extreme dry periods will become more common in Germany. At the same time the spring run-off period will grow shorter. As a result, snow packs will melt much quicker and instead of recharging the groundwater will flow directly into the rivers. This can result in a rise in the number of floods, while at the same time the natural groundwater recharge will decline. This is a long-term trend which we can, however, already observe today. In the northern part of Bavaria in particular these developments are having very alarming impacts. The Franconian dry plateau ("Fränkische Trockenplatte"), which includes the cities of Würzburg and Schweinfurt, is traditionally an arid area with very limited groundwater reserves. This region is surrounded by highlands where many clouds shed their moisture in the form of rain. As a result, the groundwater reserves can't be recharged as quickly. Together with the impacts of climate change, today we’re already seeing increasing conflicts on use between agricultural irrigation requirements, the requirements of public drinking water supplies while also ensuring minimum ecologically base flows in rivers.

So this means we should conserve water?

Conserving water makes good sense in general. But we can't forget that our conservation measures also have to be compatible with the existing water infrastructure. If we save too much, less water flows through the pipes, which might mean water stagnation that results in hygienic problems with drinking water. And less water also means more concentrated wastewater, which can lead to formation of deposits in sewage systems and thus to high levels of corrosion. A minimum flushing effect is needed in order for the system to work properly. Of course other solutions would also be conceivable, but retooling this infrastructure, which has evolved over the course of 100 years or more, is no easy thing. And in many cities these infrastructures are also outdated and investments are urgently needed that are however only being pursued half-heartedly.

„Do we really need the highest possible water quality when cleaning our houses, flushing toilets and irrigating greenery or in agriculture? ”

What are possible solutions?

Every location is different and therefore calls for water solutions that are adapted to local circumstances. This means that future-oriented solutions for our water infrastructure also look very different. We can also question whether we have to always use potable water for every application. Do we really need the highest possible water quality when cleaning our houses, flushing toilets and irrigating greenery or in agriculture? Instead we should provide a water quality that fits the application. Today purified wastewater effluents have such a high quality that they can be directly discharged into our rivers. Of course, there are still several substances in these discharges that we don't want to have. For example, the conventional wastewater treatment processes do not entirely remove residual pharmaceuticals and pathogenic germs. In order to produce a quality level suitable for a large number of possible reuses, this means the water has to be treated further. We've developed new processes for this purpose.

What’s special about these processes?

We're driven by the desire to develop processes that are taking advantage of natural principles, are energy-efficient, have a low carbon footprint, and are low in producing waste materials. In the SMART process we are modifying operational conditions in such a way that we select for high-performance bacteria that are very good at breaking down trace organic chemicals and pathogenic germs that would survive in conventional treatment systems. Where very flexible solutions are required for instance due to seasonal demand variations, we combine physical separation methods like ceramic membranes with chemical processes such as ozonation. Ceramic membranes are expensive to buy, but their 20-year life expectancy is comparatively long. This results in lower costs over the entire life cycle, so the investment pays off in the end. The membrane is a very reliable barrier and filters out the pathogens, while any remaining trace organic chemicals are removed by ozone.

Are these procedures already in use?

We’re conducting a feasibility study in the Schweinfurt region where the need for alternative solutions has been recognized and there is great interest in adopting this approach. In order to implement unconventional solutions requires a dialogue with all stakeholders to discuss advantages and disadvantages with them. We're also currently preparing a demonstration project to investigate the technical feasibility for the region. Agriculture is an important stakeholder, since fruit crops and medicinal herbs have been grown in Schweinfurt for over 100 years, and these crops require irrigation. In order to address seasonal demand variations these irrigation systems and subsequent water treatment processes have to operate in a highly dynamic way and ideally will function remote less. This is why we're employing the latest in sensor technologies and cloud-based approaches which is considering weather forecast data and measured values in real-time and integrate them in control processes.

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Research news stefanie.reiffert@tum.de news-35857 Thu, 06 Feb 2020 10:00:00 +0100
Bumble bees prefer a low-fat diet https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35873/ Bees are an important factor for our environment and our sustenance. Without insect pollination, many plant species – including various crops – cannot reproduce. “Bee mortality therefore affects food supply for human beings,” stated Professor Sara Leonhardt, who specializes in plant-insect interactions. All of the worldwide more than 20,000 bee species need to be considered. Among these, bumble bees are of particular importance besides the famous honey bee.

“Bees obtain most of their nutrients from their main food sources, which are nectar and pollen. While nectar is mainly a source of carbohydrates, pollen contains most of the other necessary nutrients: proteins, fat, minerals and vitamins. Until today, most bee researchers assumed that bees, like other herbivores, mainly consider the protein content when choosing their food,” Professor Leonhardt explained.

Using a two-step mechanistical approach that included learning and feeding experiments, the group established a new way to literally keep a close eye on the feeding habits of insects.

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Research news katharina.baumeister@tum.de news-35873 Wed, 05 Feb 2020 14:00:00 +0100
Hepatitis B: New therapeutic approach https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35885/ Around 260 million humans, more than three percent of the world's population, are chronically infected by the hepatitis B virus. As a result, every year, 880,000 people worldwide die of liver failure or hepatocellular carcinoma. Currently no curative therapy is available. The therapies available to date inhibit virus replication, but need to be given long-term. As long as infected people cannot form an adequate immune response, the virus will survive. This is precisely where Prof. Ulrike Protzer, head of the Institute of Virology at TUM and Helmholtz Zentrum München, and her team start.

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Research news news-35885 Tue, 04 Feb 2020 09:33:00 +0100
Ban Ki-moon at the TUM Speakers Series https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35889/ Ban Ki-Moon (75) once said that it was his childhood experiences during the Korean War and the subsequent help from the United Nations in rebuilding the country that motivated him to enter politics. The South Korean politician spent almost 40 years in the foreign ministry of his country and served as foreign minister from 2004 onward.

In 2007 Ban Ki-moon was elected the eighth Secretary General of the United Nations. He was leading in bringing about agreement in the United Nations on the 17 Sustainable Development Goals in 2015. A year later he was an important driving force behind the adoption of the Paris Climate Agreement.

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Event klaus.becker@tum.de news-35889 Tue, 04 Feb 2020 08:43:40 +0100
Training for safety in healthcare https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35884/ Thanks to modern medical research, patients today benefit from a high quality of care. At the same time, processes in hospitals are becoming more and more complex, and even minor errors by staff, in the organization or in technology can have far-reaching consequences for patients. As a result, hospitals and other medical facilities are increasingly in need of personnel trained in patient safety.

There is currently no specific training for patient safety in Germany. Together with TUM's University Hospital Klinikum rechts der Isar (MRI) and Klinikum Sankt Elisabeth Straubing, TUM is meeting this demand with the advanced master's program "Safety in Healthcare" and by doing so has accomplished real pioneering work for the European continent. The president of TUM, Prof. Thomas F. Hofmann, the medical director of the TUM Klinikum rechts der Isar, Prof. Markus Schwaiger, and the dean of the TUM Faculty of Medicine, Prof. Bernhard Hemmer, are pushing ahead with the joint planning for this course, which is unique in Germany. Prof. Pascal Berberat, dean of studies at the TUM Faculty of Medicine, Dr. Angelika Werner, head of the Department for Quality and Risk Management at Klinikum Rechts der Isar, and  Klinikum St. Elisabeth are working together on the design of the new course. TUM is thus expanding its commitment to Straubing as a city of science to include medical education as a future discipline.

For Bavaria's Minister of Science Bernd Sibler, the joint effort from TUM and Straubinger Klinikum is a "telling example of the high level of innovation at universities, which respond to current challenges with their degree programs." At the same time, the cooperation shows that the two clinics are committed to to continuously improve the training of medical personnel in order to provide patients with the best possible care.

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Campus news news-35884 Mon, 03 Feb 2020 15:33:30 +0100
Summit meeting on leading-edge technologies https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35883/ The state government intends to invest approximately 2 billion euros in the coming years in advanced technologies such as AI, infrastructure and support for start-ups and technology companies, and in infrastructure and the modernization of universities. TUM will play an important role in these efforts. For example, its Munich School of Robotics and Machine Intelligence (MSRM) will serve as the foundation for creating a Bavarian "KI Mission Institute" that will bundle research and entrepreneurial activities. More than 1000 representatives of the various fields and players involved in the "high-tech agenda" got together today at the TUM Garching Campus for a high-tech summit. They came from top research institutions and universities, for example, as well as government agencies, start-ups and established companies.

On the agenda, along with demonstrations of AI applications, were discussion sessions on such topics as “High tech in urban and rural settings” and “Leading-edge research at Bavarian universities”. The Bavarian Minister President Dr. Markus Söder said, “A successful future will be possible only with science. We are experiencing a new era of global competition. But instead of an arms race, it's about technology and research.” TUM President Thomas F. Hofmann stressed the importance of the humanities for engineering and applied sciences: “We cannot lose the backing of society. That's why it is essential to integrate social sciences into our degree programs at an early stage. That will ensure that students learn how to abide by ethical and moral principles and what it means to be a truly European engineer.”

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Campus news news-35883 Mon, 03 Feb 2020 13:17:00 +0100
IT security for the quantum computing age https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35881/ Cryptography is already used in cars and industrial control equipment today: Communication between the various components is encrypted. This is intended to prevent the transfer of malware through maintenance interfaces, for example. In a vehicle, hackers could disrupt safety systems, perhaps causing the brakes to be slammed on while driving at full speed. Cyber attacks on industrial facilities could lead to the theft of knowledge on production processes or the shutdown of entire factories. As electronic systems become even more tightly networked in the future, IT security for software and hardware will become increasingly important.

However, with the steady advances in the development of quantum computers, many encryption algorithms could become ineffective in the foreseeable future. Although conventional encryption tools such as elliptical curve cryptography are unbreakable for today's computers, quantum computers would be quite capable of cracking them.

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Research news paul.hellmich@tum.de news-35881 Wed, 29 Jan 2020 10:56:01 +0100
Biological diversity as a factor of production https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35872/ The main question addressed by the study is: Does greater biodiversity increase the economic value of managed ecosystems? “We have found that the possible relationships between economic value and biodiversity are varied,” says Professor Thomas Knoke, Head of the Institute of Forest Management at the TUM School of Life Sciences Weihenstephan.

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Research news katharina.baumeister@tum.de news-35872 Thu, 30 Jan 2020 08:09:00 +0100
Guardian angel of the eye https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35879/ The refractive power of the human eye lens stems from a highly concentrated protein solution. These proteins are created during embryonic development and must then function for a whole life, as the lens has no machinery to synthesize or degrade proteins.

When lens proteins are damaged, the result is cataract – a clouding of the lens – or presbyopia. This is where protective proteins come in: They ensure that the proteins of the eye retain their form even under adverse environmental influences.

"The two protective proteins αA- and αB-crystallin make up around 30 percent of the proteins in the human eye and are extremely important for the function of the lens," says Christoph Kaiser, first author of the publication in the journal Nature Structural and Molecular Biology.

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Research news battenberg@zv.tum.de news-35879 Wed, 29 Jan 2020 09:09:10 +0100
Gene scissors against incurable muscular disease https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35876/ Muscles need dystrophin in order to regenerate. Persons suffering from Duchenne muscular dystrophy lack this essential muscular protein due to mutations in the gene which is responsible for producing dystrophin. As a result, their existing muscle cells deteriorate over time and are gradually replaced by connective and fatty tissue; muscle strength weakens during the course of the disease. The first symptoms usually appear around the age of five. Children with the disease begin to have difficulties with movements they previously completed with ease, for example climbing stairs or getting up from the floor. At approximately the age of twelve, they are no longer able to walk, later losing movement in their arms and hands. Due to concomitant respiratory and cardiac failure, the majority of patients does not reach the age of 40. DMD affects mainly boys, since the responsible mutations are located in the dystrophin gene on the X chromosome.

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Research news news-35876 Tue, 28 Jan 2020 10:03:00 +0100
A real alternative to crude oil https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35874/ Polyamides are important plastics. They can be found in ski bindings and in cars or items of clothing. Commercially, they have been made predominantly from crude oil up until now; there are just a few “green” alternatives, such as polyamides based on castor oil.

Bio-based compounds are often significantly more expensive to produce and have therefore only been able to penetrate the market before now if they have had particular properties.

A team led by Volker Sieber, Professor of the Chemistry of Biogenic Raw Materials at TU Munich, has now developed a completely new polyamide family which can be produced from a byproduct of cellulose production.

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Research news battenberg@zv.tum.de news-35874 Mon, 27 Jan 2020 10:40:49 +0100
Digital Fertilization https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35870/ Up until now, farmers have calculated the amount of fertilizer per field on the basis of average yield and average soil quality. However, soil properties, yield potential and fertilizer needs may vary within limited areas, even within a single field. In places that deviate from the field's mean, plants therefore receive too much or too little fertilizer. Excess nitrogen remains in the soil, accumulating over the years and eventually escaping into the environment, for example into the groundwater.

Professor Kurt-Jürgen Hülsbergen, chair of Organic Agriculture and Agronomy, is certain: “The fertilizer needs of crop plants will increasingly be calculated using sensor-based systems and fertilization algorithms.”

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Research news katharina.baumeister@tum.de news-35870 Wed, 22 Jan 2020 08:08:00 +0100
Pretty with a twist https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35868/ Designing components for molecular self-assembly calls for functionalities that ‘interlock’. For example, our genetic information is encoded in two DNA strands, zipped together in a ‘spiral staircase’ double helix structure in a self-assembly process that is stabilized by hydrogen bonding.

Inspired by nature’s ‘zippers’ researchers at the Technical University of Munich aim to construct functional nanostructures to push the boundaries of man-made structures.

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Research news battenberg@zv.tum.de news-35868 Thu, 16 Jan 2020 09:07:46 +0100
A life's work for stem cell research https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35865/ Outstanding personalities are the life's blood of science. What motivates them? What have they experienced? What thoughts and ideas do they want to pass on to others? "Tech-Histories Alive" spotlights the answers to these questions from outstanding retired scientists appointed by TUM as Emeriti of Excellence.

Prof. Christian Peschel held the Chair of Hematology and Internal Oncology and was Director of the III. Medical Clinic of TUM’s Klinikum rechts der Isar from 1997 until his retirement in 2017. Before that he held positions at the university hospitals in Mainz and Innsbruck and conducted research at the Laboratory of Immunology of the National Institutes of Health (NIH) in the USA. Peschel has been a member of numerous professional societies and advisory bodies, including the Central Commission for Somatic Gene Therapy of the German Medical Association.

TUM's Munich Center for Technology in Society co-organizes "Tech-Histories Alive". The center conducts research, teaches and promotes public dialog on the mutual interactions of science, technology and society.

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Event klaus.becker@tum.de news-35865 Tue, 14 Jan 2020 10:45:31 +0100
Science and society in transition https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35863/ The TUM School of Governance, established in 2017, is dedicated to research and education on the interactions of politics and technology, which play a decisive role in almost all political spheres today. With this special focus of its research and teaching activities, the school makes a vital contribution to the ability to understand and shape societal change resulting from rapid technological developments. The school works in conjunction with the Bavarian School of Public Policy, which is hosted by TUM.

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Event klaus.becker@tum.de news-35863 Fri, 10 Jan 2020 12:22:00 +0100
Emergence of calorie burning fat cells https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35859/ Our fat cells, technically referred to as adipocytes, play an essential role in regulating energy balance in our body. “Adipocytes are not merely an energy storage for times of deprivation, but they also release hormones into the blood, regulating our metabolism as well as feelings of hunger and satiety through the brain and other organs. Nevertheless, too much of a good thing causes harm.” explained Professor Klingenspor, Chair of Molecular Nutritional Science at the TUM Else Kröner-Fresenius Center.

White, beige or brown – the color of fat cells affects our health

There are different types of fat tissue in our body, which can be categorized according to color. White fat cells are primarily responsible for energy storage. Brown and beige fat cells can convert nutritional energy into heat. This process is referred to as non-shivering thermogenesis – a principle that small mammals and human newborns use to maintain a stable body temperature.

The occurrence and activity of brown and beige fat cells vary among individuals. There is some evidence suggesting that people with a high number of thermogenic fat cells possess a lower risk to develop obesity and associated metabolic disorders. Especially the growth of beige fat cells within white fat tissue may have particular health benefits.

Browning ability of white fat is genetically determined

“We want to understand how thermogenic fat cells develop; so how beige fat cells grow inside white fat tissue,” stated Klingenspor. By “browning” the white fat tissue, an energy-storing organ could be partially transformed into an energy-dissipating organ, thereby improving metabolic health.

The development of beige fat cells is controlled by a still largely unknown genetic program. Mouse strains with divergent genetic backgrounds largely differ in their ability to brown the white fat tissue. “By systematically comparing fat cells among these different strains of mice, we were able to discover which genes or regulators might explain the variation in beige cell differentiation – in other words, the growth of beige fat cells”, indicated Klingenspor.

New possibilities due to transcriptomics and network analyses

By sequencing all transcripts of a cell using Next Generation Sequencing technology, all gene activities across the entire genome can be registered in a snap-shot.

For the current study, the joint TUM/EPFL team performed a comparative analysis of the transcriptomics of fat cells from genetically divergent mouse strains. The study goes beyond other work in this field in that it not only identifies important individual factors but also relates them to each other in a molecular network.

With this approach, the team could provide a systematic overview over the network of cell-intrinsic regulatory mechanisms that represent the underlying principle for the development of beige fat cells, making them the first team of scientists to achieve this.

“Now we have gathered a unique insight into the genetic architecture driving the molecular mechanisms of beige fat cell development. What we managed to confirm in a cell culture is now to be examined ‘in vivo’ – so inside a living organism – as our next step,” said Klingenspor with respect to avenues for future research.

 

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Research news katharina.baumeister@tum.de news-35859 Thu, 09 Jan 2020 08:00:00 +0100
New Hubble constant measurement using cosmic lenses https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35861/ Knowing the precise value for the Hubble constant, a measure for how fast the universe expands, is important for determining the age, size, and fate of our cosmos. Unraveling this mystery is one of the greatest challenges in astrophysics.

An international team, led by Sherry Suyu, professor at the Technical University of Munich (TUM), group leader at the Max Planck Institute for Astrophysics (MPA) and visiting scholar of the Academia Sinica Institute of Astronomy and Astrophysics in Taipei, Taiwan, has now measured the universe's expansion rate completely independent of previous methods.

This latest value for the Hubble constant represents the most precise measurement yet using gravitational lensing, where the gravity of a foreground galaxy acts like a giant magnifying lens, amplifying and distorting light from background objects. Through the lensing effect, multiple images of the same background object appear around the foreground galaxy.

Depending on the position of the object behind the foreground galaxy, the light of the different images has to travel over unlike distances to reach the observer. Brightness fluctuations of the background object therefore arrive at different times for each of the multiple images. The time delay can be measured in lensed quasar systems, where quasars are extremely distant cosmic streetlights produced by active black holes.

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Research news battenberg@zv.tum.de news-35861 Wed, 08 Jan 2020 19:22:40 +0100
Season's greetings and a happy new year https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35855/  

 

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Campus news news-35855 Tue, 24 Dec 2019 00:00:00 +0100
Climate-friendly energy from waste heat https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35853/ Every day enormous quantities of energy go to waste in industry and the transportation sector. Waste heat is generated in production processes and by motors. To utilize this heat, a team at the TUM Chair of Energy Systems has developed a new technology that can be used to generate power in factories, combined heat and power (CHP) stations, on ships and in many other industrial processes.

The easy-to-install module uses a technology similar to that of traditional steam-driven turbines. Instead of water, however, it uses an organic fluid with a lower boiling point. This principle, referred to as the Organic Rankine Cycle (ORC), was used by the team to develop a technology that makes efficient use of small quantities of waste heat with relatively uncomplicated equipment.

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Entrepreneurship news-35853 Fri, 20 Dec 2019 10:19:40 +0100
Using AI to understand the spread of cancer https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35844/ More than 90 percent of cancer patients die of distal metastases rather than as a direct result of the primary tumor. Cancer metastases usually develop from single disseminated cancer cells, which evade the body’s immune surveillance system. Up to now, comprehensive detection of these cells within the entire body has not been possible, owing to the limited resolution of imaging techniques such as bioluminescence and magnetic resonance imaging (MRI). This has resulted in a relative lack of knowledge of the specific dissemination mechanisms of diverse cancer types, which is a prerequisite for effective therapy.

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Research news news-35844 Wed, 18 Dec 2019 09:58:00 +0100
How stable are ancient structures? https://www.tum.de/die-tum/aktuelles/pressemitteilungen/details/35843/ In the 1960s a column of the Hagia Tekla Basilica cistern in Turkey collapsed and had to be replaced with a concrete pillar. Other columns of the ancient structure have suffered over time as well. In order to assess the danger of their collapsing experts have to know which forces are acting within the structure. But how can this be done in a non-intrusive manner?

"Engineering practice very often employs the Finite Element method for calculating a structure's stress state," explains Dr. Stefan Kollmannsberger of the TUM Chair for Computation in Engineering. "For example, before a bridge is built, engineers have to know whether or not the planned structure will be able to withstand the load resulting from road traffic. Engineers need proof that both the expected deformations and the stress placed on the material are within defined threshold values."

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Research news stefanie.reiffert@tum.de news-35843 Tue, 17 Dec 2019 12:26:00 +0100