Staff member of the virology department at TUM evaluating the antibody tests.
Staff member of the virology department at TUM evaluating the antibody tests.
Image: argum/Klinikum rechts der Isar
  • Covid-19, Research news
  • Reading time: 2 MIN

Antibody tests against SARS-CoV-2 are designed to improve employee and patient safetyLarge Antibody Study at the Klinikum rechts der Isar

One of the largest antibody studies against SARS-CoV-2 in Germany has begun at the university hospital Klinikum rechts der Isar at Technical University of Munich (TUM). The employee study is intended to provide data on the stability of antibodies over two years and thereby help in identifying starting points for the further improvement of protective measures for both employees and patients.

The new antibody study examines blood samples taken from employees at the Klinikum rechts der Isar at TUM and associated scientific institutes at TUM. Approximately 7,000 employees can voluntarily participate in the prospective cohort study.

The objective of the study is to determine the specific antibody status for SARS-CoV-2 and its stability over two years. A questionnaire will be used to ascertain the infection risks which the employees of the hospital have been exposed to, both at COVID-19 wards and normal wards or in other areas, such as logistics or administration. The results of the study will provide important information on employee protection and will make it possible to optimize the extensive protective measures for patients and staff in German hospitals.

Prof. Knolle (l.) and Prof. Lingor (r.) lead the antibody study for employees of the university hospital Klinikum rechts der Isar.
Prof. Knolle (l.) and Prof. Lingor (r.) lead the antibody study for employees of the university hospital Klinikum rechts der Isar.
Image: M. Hautmann

“As we expect additional waves of the pandemic, the investigations will be conducted several times during its course,” explains Percy Knolle, Professor of Molecular Immunology at TUM. He is leading the study in collaboration with Prof. Paul Lingor, Senior Physician at the TUM Neurological Clinic. “We will perform a total of four examinations every six months within a period of two years,” says Prof. Knolle.

The specific immunity to SARS-CoV-2 after surviving an infection will make it possible to estimate how long the antibodies can protect against renewed infection. At the present time, the data on this are still scarce worldwide. Prof. Lingor explains: “We hope that we can motivate as many of the employees at the Klinikum rechts der Isar as possible to take part in this important investigation. The actual personally-identifiable results of the serological testing are, of course, only communicated to the employees themselves.”

Corporate Communications Center

Technical University of Munich

Contacts to this article:

Prof. Dr. Percy Knolle
Technichal University of Munich
Institute of Molecular Immunology and Experimental Oncology
phone: +49 (0) 89 4140 - 6921
percy.knolle(at)tum.de

Prof. Dr. Paul Lingor
Technichal University of Munich
Neuro-Kopf-Zentrum
phone: +49 (0) 89 4140 - 4630
paul.lingor(at)tum.de

Article at tum.de

Dr. Bastian Höchst in the laboratory

Improving immunotherapy for cancer

One of the reasons why cancer develops is because regulatory cells inhibit the body's immune defense. Researchers under the helm of the Technical University of Munich (TUM) have discovered a mechanism for identifying...

Person wachting at a smartphone

Encryption system for a secure contact tracing app

In the fight against Covid-19, an interdisciplinary research team at the Technical University of Munich (TUM) has developed a model for a contact tracing app that protects personal data. The concept is based on an...

Prof. Wall (r) and Dr. Biehler at work on their virtual lung model.

Computer model enables protective ventilation

The use of mechanical ventilation can save lives – and not just for COVID-19 patients who develop severe respiratory problems. But at the same time, the ventilation pressure puts immense stress on delicate lung tissue....

Scientists will collect biodata using in-ear sensors

In-ear sensors to help in fight against COVID-19

A team at the Technical University of Munich (TUM) plans to use high-tech biometric sensors for 24-hour monitoring of COVID-19 patients in home isolation. The goal of the study is to find out whether rapid treatment in...

Professor Ulrike Protzer, director of the Institute of Virology at TUM, joins the state government's expert council.

Prof. Protzer joins expert council on Corona crisis

At a press conference today, Bavaria's Minister President Dr. Markus Söder and Minister of Science and Art Bernd Sibler announced the appointment of an expert council in preparation for upcoming political decisions during...

In the university hospital TUM Klinikum rechts der Isar, drugs against Covid-19 are tested.

Medications against coronavirus in trial

The university hospital is participating in studies on new medications for people suffering from Covid-19. As part of a clinical study, patients can be treated with medications that are still under development. 50 patients...