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29.01.2015, Menschen
TU München distinction for research on bioactive natural substances

Christian Hertweck awarded Wilhelm Manchot Professurship

Prof. Kai-Olaf Hinrichsen, Prof. Christian Hertweck, Prof. Michael Groll – Photo: Andreas Battenberg / TUM

The Chemistry Department of the Technische Universität München (TUM) and the Jürgen Manchot Foundation have awarded Jena chemist Professor Christian Hertweck the 2014 Willhelm Manchot Research Professorship. With this distinction, the TUM honors the chemist’s ground-breaking work on bioactive natural substances.

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21.01.2015, Research news
Computational approach reveals hidden cell subpopulations

Mathematics improve single-cell analysis

More than 40% of all genes in the experiment were significantly correlated to a small set of known cell-cycle markers (orange) - Graphic: Florian Büttner

A new computational approach allows to account for confounding factors and hidden biological processes in the analysis of single-cell RNA sequence data. Using this method, individual subpopulations and cell types can be identified within heterogeneous cell populations and can be determined more precisely. Scientists from Helmholtz Zentrum München (HMGU) and Technische Universität München (TUM), together with colleagues from the European Bioinformatics Institute (EBI), have now reported these findings in the journal Nature Biotechnology.

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20.01.2015, Research news
Study investigates impact of catastrophic 2013 flooding on grassland habitat

Fields with high diversity benefit from being submerged

[Translate to en:] Die Flut 2013 zeigte den Wissenschaftlerinnen und Wissenschaftlern des Jena Experiments, dass artenreiches Grasland von Überschwemmungen profitieren kann.

Extreme weather events are becoming more frequent because of climate change. European countries will have to expect further catastrophic flooding on a similar scale to June 2013. Now a research team involving scientists from TUM has discovered that grassland with high diversity actually benefits from inundation. When a high number of species are present, grassland becomes more effective at converting the influx of resources from the flood water into biomass. The study was published in Nature Communications.

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14.01.2015, Research news
Researchers measure how electrons move through single atomic layers

Rapid journey through a crystal lattice

Prof. Kienberger at the attosecond beamline where the experiments were conducted – Photo: Thorsten Naeser / MPQ

How fast do electrons whiz through the atomic layers of a crystal lattice? A team of scientists led by researchers from the Technische Universität München (TUM) joined by colleagues from the Max Planck Institute of Quantum Optics (MPQ), the Ludwig-Maximilians-Universität Munich and the Technical University of Vienna has now investigated this fundamental question. The researchers measured the time electrons needed to travel through a film consisting of a few layers a of magnesium atoms.

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08.01.2015, Termin
Thu. Jan. 15, 5pm: Public talk on the brain's own positioning system

Nobel laureate Edvard Moser explains our "sense of space"

Prof. Edvard Moser during a visit to TUM in October 2014 (Photo: Astrid Eckert / TUM).

How do we know where we are? The search for answers led to the 2014 Nobel Prize in Physiology or Medicine, and insights from this trail-blazing neuroscience research could inspire future technological breakthroughs. In a public lecture at the Technische Universität München (Thursday Jan. 15, 17:00), Nobel laureate Edvard Moser will explain what he and colleagues have discovered about the brain's own positioning system.

 

 

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08.01.2015, Research news
Regulatory T cells need T cell receptor to fulfill protective functions

T cell receptor ensures Treg functionality

Christoph Vahl, lead author of the study, investigates Tregs and the role of their T cell receptor. (Photo: C. Vahl / TUM)

Misdirected immune responses that target the body’s own tissue can result in human diseases. Regulatory T cells known as Tregs combat this effect by suppressing excessive immune responses and responses against our own bodies. Until now, scientists had been aware of two molecular properties of Tregs that control these protective functions. Researchers at Technische Universität München (TUM) have now shown that signals emitted by T cell receptor on the surface of Tregs are also essential for their identity and suppressive functions.

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29.12.2014, Research news
Positrons answer questions on targeted release of medication

Gummy bears under antiparticle fire

Gummy bear on the experimental set-up – Photo: Wenzel Schürmann / TUM

Gelatin is used in the pharmaceutical industry to encapsulate active agents. It protects against oxidation and overly quick release. Tiny pores in the material have a significant influence on this, yet they are difficult to investigate. In experiments on gummy bears, researchers at Technische Universität München (TUM) have now transferred a methodology to determine the free volume of gelatin preparations.

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23.12.2014, TUM in Rankings
TUM School of Management now ranks third among German-speaking universities

Business studies at TUM remain unbeaten nationwide

Prof. Gunther Friedl, Dean of the TUM School of Management, with students.

The leading business newspaper Handelsblatt has again rated business studies at the Technische Universität München (TUM) the best in Germany. Among all German-speaking universities, the TUM School of Management ranked third, moving ahead two places in comparison to the last ranking in 2012. Only the Swiss universities of St. Gallen and Zürich did better.

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18.12.2014, Research news
New disease mechanism discovered in lymphoma

Mutations prevent programmed cell death

Fluorescence microscopy image showing the ubiquitin ligase FBXO25 (green) and the “life-preserving” protein (red) in a cancer cell that is currently undergoing programmed cell death. The yellow signal indicates instances where both proteins are at the same location. (Picture: F. Bassermann / TUM)

Programmed cell death is a mechanism that causes defective and potentially harmful cells to destroy themselves. It serves a number of purposes in the body, including the prevention of malignant tumor growth. Now, researchers at Technische Universität München (TUM) have discovered a previously unknown mechanism for regulating programmed cell death. They have also shown that patients with lymphoma often carry mutations in this signal pathway.

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17.12.2014, Research news
Self-healing concrete to improve the durability of structures

HEALCON project develops innovative construction materials

Technician sticks ultrasound sensors onto a concrete beam. (Picture: Werner Bachmeier / TUM)

Manual repairs to structures lead to endless traffic jams everywhere, but imagine that all this misery on the road could be eliminated by means of concrete that repairs itself. That is exactly what the European project HEALCON aims to achieve, the development of self-healing concrete to improve the durability of structures.

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