New research results or upcoming events: Stay up-to-date on what is happening at TUM.
TUM would like to wish you and your family happy holidays and a great start to the New Year. We would like to take this opportunity to thank everyone who has helped make 2014 a great year for TUM, including our students and employees, our alumni and friends of TUM around the world. We wish you a healthy and happy 2015!
Programmed cell death is a mechanism that causes defective and potentially harmful cells to destroy themselves. It serves a number of purposes in the body, including the prevention of malignant tumor growth. Now, researchers at Technische Universität München (TUM) have discovered a previously unknown mechanism for regulating programmed cell death. They have also shown that patients with lymphoma often carry mutations in this signal pathway.
Manual repairs to structures lead to endless traffic jams everywhere, but imagine that all this misery on the road could be eliminated by means of concrete that repairs itself. That is exactly what the European project HEALCON aims to achieve, the development of self-healing concrete to improve the durability of structures.
Children who suffer from Hutchinson-Gilford Progeria Syndrome (HGPS) age prematurely due to a defective protein in their cells. Scientists at Technische Universität München (TUM) have now identified another important pathological factor: the system responsible for removing cellular debris and for breaking down defective proteins operates at lower levels in HGPS cells than in normal cells. The researchers have now succeeded in reactivating protein breakdown in HGPS cells and thus reducing disease-related defects with the help of a substance found in broccoli.
Technische Universität München (TUM) achieved eighth place in the ranking table, cementing its excellent reputation as an educational institute for young academics who are much sought after in international job markets. The ranking is based on a survey of almost 5,000 HR managers and employers from industry and commerce in 20 different countries. The most recent results have been published in The New York Times and The Telegraph.
The European Institute of Innovation and Technology (EIT) has announced a new future-oriented project that has emerged the winner of a pan-European competition: EIT Health, with international headquarters on the Garching campus of TU München. A total of 144 industrial and scientific partners from a number of EU countries will join forces to investigate key health issues. TUM is one of the core German partners. The EU is sponsoring the project as a Knowledge and Innovation Community (KIC) for seven years to the tune of around 80 million euros per year. One of the Co-Location Centers distributed across Europe is in Heidelberg. The proposal was prepared by a consortium under the leadership of Roche Diagnostics GmbH.
Unlike mammals, birds have no external ears. The outer ears of mammals play an important function in that they help the animal identify sounds coming from different elevations. But birds are also able to perceive whether the source of a sound is above them, below them, or at the same level. Now a research team from Technische Universität München (TUM) has discovered how birds are able to localize these sounds, namely by utilizing their entire head. Their findings were published recently in the PLOS ONE journal.
Prof. Dr. Hendrik Dietz from the Technische Universität München (TUM) has been awarded the Gottfried Wilhelm Leibniz Prize of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation). The 36-year-old biophysicist is thus the recipient of Germany’s most prestigious research award, which is endowed with 2.5 million euros. Hendrik Dietz is being honored for his internationally-renowned work in the field of bionanotechnology. His research into the mechanical and structural properties of proteins has opened up completely new horizons for the development of DNA-based “nanomachines”.
Because food crops are also used for energy production, millions of people are threatened by starvation. Algae could provide an alternative: They only need sunlight to grow, thrive in salty water on barren fields. But it is a major challenge to exactly reproduce sunlight in the laboratory. In collaboration with the Berlin LED manufacturer FUTURELED scientists at the Technische Universität München (TUM) have now developed a methodology for simulating all kinds of light situations.
A new substance that unifies the action profiles of three gastrointestinal hormones lowers the blood sugar level and reduces body fat considerably beyond existing drugs. With the discovery and validation of such novel molecules, scientists from the Helmholtz Zentrum München (HMGU) and Technische Universität München (TUM), in collaboration with Indiana University have again added a new dimension to innovating treatment approaches for type 2 diabetes and obesity. Recently, the researchers had constructed several single molecules with dual hormone action.