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19.12.2014, Campus news
Happy holidays and best wishes for 2015

Holiday greetings from TUM

Germany’s highest research center on the Zugspitze mountain: Schneefernerhaus environmental research station (Photo: Markus Neumann, UFS GmbH)

TUM would like to wish you and your family happy holidays and a great start to the New Year. We would like to take this opportunity to thank everyone who has helped make 2014 a great year for TUM, including our students and employees, our alumni and friends of TUM around the world. We wish you a healthy and happy 2015!

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18.12.2014, Research news
New disease mechanism discovered in lymphoma

Mutations prevent programmed cell death

Fluorescence microscopy image showing the ubiquitin ligase FBXO25 (green) and the “life-preserving” protein (red) in a cancer cell that is currently undergoing programmed cell death. The yellow signal indicates instances where both proteins are at the same location. (Picture: F. Bassermann / TUM)

Programmed cell death is a mechanism that causes defective and potentially harmful cells to destroy themselves. It serves a number of purposes in the body, including the prevention of malignant tumor growth. Now, researchers at Technische Universität München (TUM) have discovered a previously unknown mechanism for regulating programmed cell death. They have also shown that patients with lymphoma often carry mutations in this signal pathway.

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17.12.2014, Research news
Self-healing concrete to improve the durability of structures

HEALCON project develops innovative construction materials

Technician sticks ultrasound sensors onto a concrete beam. (Picture: Werner Bachmeier / TUM)

Manual repairs to structures lead to endless traffic jams everywhere, but imagine that all this misery on the road could be eliminated by means of concrete that repairs itself. That is exactly what the European project HEALCON aims to achieve, the development of self-healing concrete to improve the durability of structures.

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17.12.2014, Research news
Hutchinson-Gilford Progeria Syndrome: New findings from human cell cultures

Progeria research: Substance from broccoli can moderate defects

The image shows two cell nuclei containing human DNA (blue). Because of the large quantity of progerin (red), the nuclei in the cells of HGPS patients (left) are deformed in comparison to nuclei with very low levels of progerin (right). (Photo: K. Djabali / TUM)

Children who suffer from Hutchinson-Gilford Progeria Syndrome (HGPS) age prematurely due to a defective protein in their cells. Scientists at Technische Universität München (TUM) have now identified another important pathological factor: the system responsible for removing cellular debris and for breaking down defective proteins operates at lower levels in HGPS cells than in normal cells. The researchers have now succeeded in reactivating protein breakdown in HGPS cells and thus reducing disease-related defects with the help of a substance found in broccoli.

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12.12.2014, TUM in Rankings
Global Employability University Ranking 2014

TUM at the top of the table

Fit for working life: TUM Students - like here in the Institute of Medical and Polymer Engineering - are much sought after in international job markets. (Photo: A. Heddergott / TUM)

Technische Universität München (TUM) achieved eighth place in the ranking table, cementing its excellent reputation as an educational institute for young academics who are much sought after in international job markets. The ranking is based on a survey of almost 5,000 HR managers and employers from industry and commerce in 20 different countries. The most recent results have been published in The New York Times and The Telegraph.

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11.12.2014, Campus news
TUM campus in Garching to become international project headquarters

EIT Health launched as a European flagship project

The international headquarters of EIT Health will be on the Garching campus of TU München. (Photo: A. Heddergott / TUM)

The European Institute of Innovation and Technology (EIT) has announced a new future-oriented project that has emerged the winner of a pan-European competition: EIT Health, with international headquarters on the Garching campus of TU München. A total of 144 industrial and scientific partners from a number of EU countries will join forces to investigate key health issues. TUM is one of the core German partners. The EU is sponsoring the project as a Knowledge and Innovation Community (KIC) for seven years to the tune of around 80 million euros per year. One of the Co-Location Centers distributed across Europe is in Heidelberg. The proposal was prepared by a consortium under the leadership of Roche Diagnostics GmbH.

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10.12.2014, Research news
Scientists discover how birds localize sound sources

How birds get by without external ears

Birds can hear without the need for external ears – and now a TUM research team has found out how.

Unlike mammals, birds have no external ears. The outer ears of mammals play an important function in that they help the animal identify sounds coming from different elevations. But birds are also able to perceive whether the source of a sound is above them, below them, or at the same level. Now a research team from Technische Universität München (TUM) has discovered how birds are able to localize these sounds, namely by utilizing their entire head. Their findings were published recently in the PLOS ONE journal.

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10.12.2014, Research news
Biophysicist Hendrik Dietz (36) awarded top German research award

Fourth Leibniz prizewinner in the TUM Physics Department

Prof. Dr. Hendrik Dietz has been awarded the Gottfried Wilhelm Leibniz Prize. (Photo: A. Eckert and A. Heddergott / TUM)

Prof. Dr. Hendrik Dietz from the Technische Universität München (TUM) has been awarded the Gottfried Wilhelm Leibniz Prize of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation). The 36-year-old biophysicist is thus the recipient of Germany’s most prestigious research award, which is endowed with 2.5 million euros. Hendrik Dietz is being honored for his internationally-renowned work in the field of bionanotechnology. His research into the mechanical and structural properties of proteins has opened up completely new horizons for the development of DNA-based “nanomachines”.

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08.12.2014, Research news
Novel LED technology enables detailed investigation of algae productivity

Put algae in your tank

Student Olga Shostak at the LED-bioreactor - Photo: Andreas Heddergott / TUM

Because food crops are also used for energy production, millions of people are threatened by starvation. Algae could provide an alternative: They only need sunlight to grow, thrive in salty water on barren fields. But it is a major challenge to exactly reproduce sunlight in the laboratory. In collaboration with the Berlin LED manufacturer FUTURELED scientists at the Technische Universität München (TUM) have now developed a methodology for simulating all kinds of light situations.

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08.12.2014, Research news
Scientists design combination of three metabolically active substance

Hormone Triplet offers Hope for Obesity and Diabetes

Prof. Matthias Tschöp and his team invent improved therapeutics for type 2 diabetes and obesity. (Photo: A. Heddergott / TUM)

A new substance that unifies the action profiles of three gastrointestinal hormones lowers the blood sugar level and reduces body fat considerably beyond existing drugs. With the discovery and validation of such novel molecules, scientists from the Helmholtz Zentrum München (HMGU) and Technische Universität München (TUM), in collaboration with Indiana University have again added a new dimension to innovating treatment approaches for type 2 diabetes and obesity. Recently, the researchers had constructed several single molecules with dual hormone action.

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