• 11/28/2022
  • Reading time 3 min.

DFG funds new projects and extends existing collaborative research centers

Three new CRCs with significant participation on the part of TUM

The German Research Foundation (DFG) has extended its funding for the Microbiome Signatures collaborative research center (CRC 1371) which is led by the Technical University of Munich (TUM). Additionally, three new projects in which TUM was an applicant university have been approved. The topics range from T-cells, to plant-microbe interactions, through to the mathematics of quantum systems.

Dirk Haller, Professor of Nutrition and Immunology, working in his lab. Andreas Heddergott / TUM
Prof. Dirk Haller (left) is the spokesperson of the Collaborative Research Center Microbiome Signatures, which the German Research Foundation is funding for another four years. In addition, three new Transregional CRCs are being funded with significant participation from TUM.

The DFG Collaborative Research Centers are among the most important research funding programs in Germany. They allow for challenging, interdisciplinary and long-term research projects. The DFG initially approves the projects for four years, and they can be funded for twelve years in total. A “Transregio” or TRR is a collaborative research center whose partners cooperate on a trans-regional basis.

Since 2019, CRC 1371, has been investigating the links between the microbiome of the human digestive tract and diseases such as cancer and inflammatory bowel diseases. The spokesperson for the interdisciplinary research project is Dirk Haller, Professor of Nutrition and Immunology at TUM, and director of „ZIEL – Institute for Food & Health“ at the Weihenstephan campus. While scientists agree that there is a close connection between the bacteria in our digestive system and our health, many of the mechanisms behind this remain unknown. One of the goals of CRC 1371 is to better understand these mechanisms, and to put them to use for the treatment and prevention of diseases. The DFG is funding the CRC for another four years.

New TRRs with TUM participation

TRR 352: Mathematics of ManyBody Quantum Systems and Their Collective Phenomena

The project addresses the mathematical analysis of models from the field of condensed matter physics. These describe the collective behavior of a large number of interacting components, such as particles or spins. Their behavior leads to a variety of macroscopically observable phenomena that have, until now, been poorly understood.

TRR 356: Genetic Diversity Shaping Biotic Interactions of Plants (PlantMicrobe)

The interactions between plants and microbes are a critical factor in the field of plant health. At the interface between plant sciences and microbiology, this TRR will use modern approaches from the fields of biochemistry, genetics as well as comparative omics analysis to gain insights so as to help improve plant health and therefore plant productivity over the long term through the optimum use of natural mechanisms.

TRR 355: Heterogeneity and Functional Specialization of Regulatory T cells in Distinct Microenvironments

Regulatory T-cells, or treg cells for short, play a key role in controlling the immune response of the human body. They are also integrated into the functional architecture of various tissues. Despite certain similarities, treg cells also have significant differences according to their function. The CRC is investigating this heterogeneity of treg cells and their influence on immunological and tissue-specific diseases. The goal is to be able to use treg cells for the development of customized immuno-therapies.

Other extended projects with TUM participation

CRC 1366: Vascular Control of Organ Function

TRR 237: Nucleic Acid Immunity

Further information and links

Technical University of Munich

Corporate Communications Center

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